Large wardrobe separates clothes (5)
I believe the answer is:
obese
'large' is the definition.
(thesaurus)
'wardrobe separates clothes' is the wordplay.
'clothes' indicates a hidden word (the letters clothe the hidden word).
'OBESE' is hidden in the letters of 'wardrobe separates'.
(Other definitions for obese that I've seen before include "Carrying far too much weight" , "Much too fat" , "porky?" , "round" , "Grossly overweight" .)