Last despite great efforts (5,3)
I believe the answer is:
after all
'last' is the definition.
(coming after everyone else)
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for after all that I've seen before include "in the final reckoning?" , "When everything is said and done" , "anyway" , "in spite of expectations to the contrary" , "Behind from start to finish" .)