Later sent out first of honey in hives (6,4)
I believe the answer is:
nettle rash
'hives' is the definition.
('nettle rash' can be a synonym of 'hives')
'later sent out first of honey' is the wordplay.
'out' is an anagram indicator (out can mean wrong or inaccurate).
'first of' suggests taking the first letters.
The initial letter of 'honey' is 'h'.
'later'+'sent'='latersent'
'latersent' anagrammed gives 'nettleras'.
'nettleras'+'h'='NETTLE RASH'
'in' acts as a link.
(Other definitions for nettle rash that I've seen before include "major irritant" , "Hives" , "Urticaria" .)