Lay out clues with endless care (7)
I believe the answer is:
secular
'lay' is the definition.
('secular' can be a synonym of 'lay')
'out clues with endless care' is the wordplay.
'out' indicates anagramming the letters.
'with' says to put letters next to each other.
'endless' means to look at the middle letters.
The middle letters of 'care' are 'ar'.
'clues' with letters rearranged gives 'secul'.
'secul'+'ar'='SECULAR'
(Other definitions for secular that I've seen before include "Not spiritual" , "Not involving religion,worldly" , "Not connected with religious matters" , "Not concerned with religion" , "Not religious or sacred" .)