Layabout seen in Salcombe every now and again (4)
I believe the answer is:
slob
'layabout' is the definition.
(both can mean a lazy person)
'salcombe every now and again' is the wordplay.
'every now and again' means one should take alternating letters.
The alternate letters of 'salcombe' are 'SLOB'.
'seen in' is the link.
(Other definitions for slob that I've seen before include "Couch potato" , "Slovenly person (colloq.)" , "Uncouth person" , "Slovenly and unkempt type" , "'Slovenly, messy person (4)'" .)