Laziness of hotel pursuing vacancy (5)
I believe the answer is:
sloth
'laziness' is the definition.
(sloth is a kind of laziness)
'hotel pursuing vacancy' is the wordplay.
'hotel' becomes 'h' (phonetic alphabet: alpha, bravo, charlie etc.).
'pursuing' says to put letters next to each other.
'vacancy' becomes 'slot' (a slot can be a vacancy in a schedule).
'h' after 'slot' is 'SLOTH'.
'of' is the link.
(Other definitions for sloth that I've seen before include "One's often suspended from tree" , "One of the seven deadly sins" , "One hangs a lot" , "Sinful" , "Jungle mammal; laziness" .)