Lead from spinning top, say (5)
I believe the answer is:
speak
'say' is the definition.
(synonyms)
'lead from spinning top' is the wordplay.
'lead from' says to take the initial letters (the letter that leads the word).
'top' becomes 'peak' (synonyms).
The first letter of 'spinning' is 's'.
's'+'peak'='SPEAK'
(Other definitions for speak that I've seen before include "Orate" , "Utter words" , "express" , "Say something" , "Talk" .)