Lead off to glen (4)
I believe the answer is:
dale
'to glen' is the definition.
(I've seen this in another clue)
'lead off' is the wordplay.
'off' indicates an anagram.
'lead' with letters rearranged gives 'DALE'.
(Other definitions for dale that I've seen before include "Up hill and down . . . ." , "Valley; man's name" , "Valley, as in Yorkshire" , "Lead into poetic valley" , "An English valley" .)