Least cool women's smallest clothes (10)

I believe the answer is:

twitchiest

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'least cool women's smallest clothes' is the definition.
I can't judge whether this definition defines the answer.

'cool women's smallest clothes' is the wordplay.
'cool women' becomes 'w' (standard abbreviation. I am not sure about the 'cool' bit.).
'smallest' becomes 'titchiest' (I've seen this before).
'clothes' is an insertion indicator (some letters clothe or cover others).
'w' going within 'titchiest' is 'TWITCHIEST'.

Can you help me to learn more?

(Another definition for twitchiest that I've seen is " most ill at ease".)

I've seen this clue in The Guardian.

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