Leave out of random items (4)
I believe the answer is:
omit
'leave out' is the definition.
(I know that leave out can be written as omit)
'of random items' is the wordplay.
'of' indicates a hidden word.
'OMIT' is hidden within 'random items'.
(Other definitions for omit that I've seen before include "Don't include" , "Fail to use" , "Leave out, perhaps in error" , "Drop" , "Take out" .)