Leave river holding record (6)
I believe the answer is:
depart
'leave' is the definition.
(I know that leave can be written as depart)
'river holding record' is the wordplay.
'river' becomes 'dart' (River Dart in Devon).
'holding' means one lot of letters goes inside another.
'record' becomes 'EP' (abbreviation for extended play record).
'dart' going around 'ep' is 'DEPART'.
(Other definitions for depart that I've seen before include "Quit" , "Leave (6)" , "Go away; deviate" , "21" , "Prated (anag.)" .)