Leave Virginia with an elk (7)
I believe the answer is:
vamoose
'leave' is the definition.
(I know that vamoose is a kind of leave)
'virginia with an elk' is the wordplay.
'virginia' becomes 'va' (US state abbreviation).
'with' says to put letters next to each other.
'an elk' becomes 'moose' ('moose' can be a synonym of 'elk').
'va'+'moose'='VAMOOSE'
(Other definitions for vamoose that I've seen before include "Scram!" , "take flight!" , "Do a runner" , "Get going: leave hurriedly" , "Beat it" .)