Lee and Ned worked in sewer (6)
I believe the answer is:
needle
'sewer' is the definition.
(I've seen this before)
'lee and ned worked' is the wordplay.
'and' means one lot of letters go next to another.
'worked' is an anagram indicator.
'lee' put after 'ned' is 'nedlee'.
'nedlee' with letters rearranged gives 'NEEDLE'.
'in' acts as a link.
(Other definitions for needle that I've seen before include "Implement for knitting and sewing" , "anger" , "Rile" , "It's vital to baste" , "Irritate, goad" .)