Left-hander (8)
I believe the answer is:
southpaw
'left-hander' is the definition.
(synonyms)
This is all the clue.
(Other definitions for southpaw that I've seen before include "To wash up (anag.)" , "Boxer who leads with the right hand" , "Unorthodox leader" , "Man with gloves on" , "Left-hander" .)