Let deep changes use everything up (7)
I believe the answer is:
deplete
'use everything up' is the definition.
I can't tell whether this definition defines the answer.
'let deep changes' is the wordplay.
'changes' indicates anagramming the letters.
'let'+'deep'='letdeep'
'letdeep' with letters rearranged gives 'DEPLETE'.
Can you help me to learn more?
(Other definitions for deplete that I've seen before include "Empty, reduce, exhaust" , "Reduce (amount of supplies etc)" , "Use up, reduce in quantity" , "Reduce the quantity of (resources)" , "Drain" .)