Let it stand about again in the road (6)
I believe the answer is:
street
'road' is the definition.
(I know that road can be written as street)
'let it stand about again' is the wordplay.
'let it stand' becomes 'stet' (I've seen this before).
'about' means one lot of letters goes inside another.
'again' becomes 're' (prefix meaning 'again').
'stet' enclosing 're' is 'STREET'.
'in the' is the link.
(Other definitions for street that I've seen before include "See 7" , "See 1 Down" , "Town road" , "Thoroughfare lined with buildings" , "See 17" .)