Like certain wines? Souse drained last of Barsac (3)
I believe the answer is:
sec
'like certain wines?' is the definition.
(I've seen this in another clue)
'souse drained last of barsac' is the wordplay.
'drained' suggests removing the centre.
'last of' says to take the final letters.
'souse' with its centre removed is 'se'.
The final letter of 'barsac' is 'c'.
'se'+'c'='SEC'
(Other definitions for sec that I've seen before include "Dry wine perhaps" , "Religious group." , "very short space of time" , "sort of function" , "Jiffy" .)