Like certain wines? Souse drained last of Barsac (3)
I believe the answer is:
sec
'like certain wines?' is the definition.
(I've seen this in another clue)
'souse drained last of barsac' is the wordplay.
'drained' means to remove the middle letters.
'last of' suggests the final letters.
'souse' with its centre removed is 'se'.
The final letter of 'barsac' is 'c'.
'se'+'c'='SEC'
(Other definitions for sec that I've seen before include "Dry wine perhaps" , "Religious group." , "very short space of time" , "sort of function" , "Jiffy" .)