Like James Hilton's Horizon (4)
I believe the answer is:
lost
'hilton's horizon' is the definition.
(I've seen this in another clue)
'like james' is the wordplay.
'like' becomes 'lo' (I can't explain this - if you can you should give a lot more credence to this answer).
'james' becomes 'St James' (synonyms).
'lo'+'st'='LOST'
Can you help me to learn more?
(Other definitions for lost that I've seen before include "TV show" , "Mislaid or strayed" , "Not recognising one's whereabouts" , "Forgotten; misplaced" , "Unable to find one's way" .)