Like NY's irregular silhouette? (7)
I believe the answer is:
skyline
'silhouette?' is the definition.
(silhouette of buildings)
'like ny's irregular' is the wordplay.
'irregular' is an anagram indicator.
'like'+'nys'='likenys'
'likenys' with letters rearranged gives 'SKYLINE'.
(Other definitions for skyline that I've seen before include "Visible horizon" , "Built-up horizon" , "Horizon; like NY's (anag.)" , "Silhouette or outline of buildings" , "Outline of hills or buildings against firmament" .)