Lions seize tablets, chair (7)
I believe the answer is:
preside
'chair' is the definition.
(synonyms)
'lions seize tablets' is the wordplay.
I cannot quite see how this works, but
'tablets' could be 'es' (E can refer to an ecstasy tablet) and 'es' is found within the answer.
'lions' could be 'pride' (pride is the collective noun for a group of lions) and 'pride' is found in the remaining letters.
This accounts for all the letters.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for preside that I've seen before include "Take the chair" , "Be chairman" , "Be in authority (over)" .)