Listed building is least occupied (6)
I believe the answer is:
idlest
'least occupied' is the definition.
'listed building' is the wordplay.
'building' is an anagram indicator.
'listed' with letters rearranged gives 'IDLEST'.
'is' is the link.
(Other definitions for idlest that I've seen before include "Most lazy" , "least fond of Labour?" , "most unused" , "Least busy and laziest" , "Most useless" .)