Crossword Genius

Literally, "fly," in Setswana

Ross

I believe the answer is:

tsetse

(Other definitions for tsetse that I've seen before include "cause of sleepiness?" , "African transmitter" , "Bloodsucking African fly" , "Disease-carrying fly" , "source of sleeping sickness" .)

I've seen this clue in The New York Times.
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