Little, almost disgusting creature (6)
I believe the answer is:
weevil
'creature' is the definition.
(weevil is a kind of creature)
'little almost disgusting' is the wordplay.
'little' becomes 'wee' ('wee' can be similar in meaning to 'little').
'almost' means to remove the last letter (most of the word but not all of it).
'disgusting' becomes 'vile' (I've seen this before).
'vile' with its final letter taken off is 'vil'.
'wee'+'vil'='WEEVIL'
(Other definitions for weevil that I've seen before include "Destructive beetle" , "Small beetle with a long snout" , "Insect pest that damages crops" , "Kind of beetle that damages crops" , "it goes against the grain!" .)