Lizard Island drifting west in South American region (6)

I believe the answer is:
iguana
'lizard' is the definition.
(iguana is a kind of lizard)
'island drifting west in south american region' is the wordplay.
'island' becomes 'i' (geographical abbreviation).
'drifting west in south american region' becomes 'guana' (I can't justify this - if you can you should give a lot more credence to this answer).
'i'+'guana'='IGUANA'
Can you help me to learn more?
(Other definitions for iguana that I've seen before include "Large tree-climbing lizard of tropical America" , "cold-blooded customer!" , "reptile" , "Arboreal lizard with a spiny crest" , "Animal" .)
