Loathe man with dodgy pies (7)
I believe the answer is:
despise
'loathe' is the definition.
(I've seen this in another clue)
'man with dodgy pies' is the wordplay.
'man' becomes 'des' ().
'with' is a charade indicator (letters next to each other).
'dodgy' indicates anagramming the letters (a dodgy or wrong order of the letters).
'pies' with letters rearranged gives 'pise'.
'des'+'pise'='DESPISE'
(Other definitions for despise that I've seen before include "Loathe, look down on" , "Abhor" , "Feel contempt for; scorn" , "Have contempt for, regard as low" , "Hate, disdain" .)