Lob extremely deficient paint all over the place, one lacking pigment (6)
I believe the answer is:
albino
'one lacking pigment' is the definition.
(person lacking pigment in hair and skin)
'lob extremely deficient paint all over the place' is the wordplay.
'extremely deficient' says to take the centre.
'all over the place' indicates anagramming the letters.
The centre of 'paint' is 'ain'.
'lob'+'ain'='lobain'
'lobain' anagrammed gives 'ALBINO'.
(Other definitions for albino that I've seen before include "Person or animal lacking pigmentation" , "Abnormally white creature" , "Man or animal lacking colouring pigment" , "Animal or plant lacking pigmentation" , "Lacking normal skin pigment" .)