Lock up bloke covered in wine (6)
I believe the answer is:
remand
'lock up' is the definition.
(as in remanding in custody)
'bloke covered in wine' is the wordplay.
'bloke' becomes 'man' (informal term for a man).
'covered in' is an insertion indicator.
'wine' becomes 'red' (red is a type of wine).
'man' going inside 'red' is 'REMAND'.
(Other definitions for remand that I've seen before include "Return prisoner to custody pending further investigation" , "Return prisoner to custody while awaiting trial" , "Place of detention for young offenders" , "Return (often) to custody" , "Place (someone) on bail or in custody" .)