Locks seat when Charlie leaves (4)
I believe the answer is:
hair
'locks' is the definition.
(locks can mean hair)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for hair that I've seen before include "Bristle" , "Human head covering" , "It grows from a follicle" , "Outgrowth from the skin" , "It grows from the skin" .)