Long time taken in Manchester again (3)
I believe the answer is:
era
'long time' is the definition.
(a long period of time)
'taken in manchester again' is the wordplay.
'taken in' indicates the answer is hidden within the clue.
'ERA' is hidden within 'manchester again'.
(Other definitions for era that I've seen before include "8" , "day" , "Important time" , "Long historic period" , "Cycle" .)