Looks for a soft fruit to fix acne (10)
I believe the answer is:
appearance
'looks' is the definition.
(thesaurus)
'a soft fruit to fix acne' is the wordplay.
'soft' becomes 'pp' (musical abbreviation for pianissimo).
'fruit' becomes 'ear' (ear is a kind of fruit).
'to fix' is an anagram indicator.
'acne' with letters rearranged gives 'ance'.
'a'+'pp'+'ear'+'ance'='APPEARANCE'
'for' is the link.
(Other definitions for appearance that I've seen before include "show" , "air" , "Outward look" , "Someone present has put one in" , "Look; impression given" .)