Loose from city to country (7)
I believe the answer is:
riotous
'loose' is the definition.
(thesaurus)
'city to country' is the wordplay.
'city' becomes 'rio' (Rio de Janeiro).
'country' becomes 'us' (U.S. is an example).
'rio'+'to'+'us'='RIOTOUS'
'from' acts as a link.
(Other definitions for riotous that I've seen before include "Unrestrained, wild living perhaps" , "Of mob, disorderly and unruly" , "Marked by public disorder" , "Anarchic" , "Artificial fabric" .)