Loose Independent clue is not to be beaten (10)
I believe the answer is:
'loose' is the definition.
('licentious' can be a synonym of 'loose')
'independent clue is not to be beaten' is the wordplay.
'independent' becomes 'i'.
'to be beaten' indicates an anagram.
'iclueisnot' with letters rearranged gives 'LICENTIOUS'.
(Other definitions for licentious that I've seen before include "disregarding accepted rules" , "Depraved" , "Abandoned" , "Promiscuous" .)