Loose-limbed, Italian male after end of drill (5)
I believe the answer is:
lithe
'loose-limbed' is the definition.
(I've seen this before)
'italian male after end of drill' is the wordplay.
'italian' becomes 'it'.
'male' becomes 'he'.
'after' means one lot of letters go next to another.
'end of' indicates one should take the final letters.
The last letter of 'drill' is 'l'.
'it'+'he'='ithe'
'ithe' put after 'l' is 'LITHE'.
(Other definitions for lithe that I've seen before include "Lissom, supple" , "grace" , "showing flexibility" , "quick to move" , "Slim, graceful" .)