Lose example of big road kill (6)
I believe the answer is:
mislay
'lose example of big road kill' is the definition.
'mislay' can be an answer for 'lose' (synonyms). I'm unsure of the 'example of big road kill' bit.
'road kill' is the wordplay.
'road' becomes 'MI' (resembles M1 motorway).
'kill' becomes 'slay' (slaying is a kind of killing).
'mi'+'slay'='MISLAY'
Can you help me to learn more?
(Other definitions for mislay that I've seen before include "Put something aside and forget where" , "Lose track of" , "Temporarily not find" , "Put in wrong place, lose temporarily" , "Lose (an item)" .)