Lose focus, with "out" (4)
I believe the answer is:
zone
'lose focus with out' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for zone that I've seen before include "Designated or defined area" , "District, area" , "Area with a particular characteristic" , "Distinctive area" , "Area subject to restrictions, parking say" .)