Lose hope (7)

I think it could be either:

despair

despond

'lose hope' is the definition.
(synonyms)

This is all the clue.

(Other definitions for despair that I've seen before include "Be without hope" , "Give up hope" , "Lose heart" , "Resignation" , "Praised (anag) - lose hope" .)

I've seen this clue in the Penny Press, the Evening Standard, the Sydney Morning Herald, The Independent, The Telegraph and The Star Tribune.

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