Losers made about a hundred in game (8)
I believe the answer is:
lacrosse
'in game' is the definition.
(I've seen this before)
'losers made about a hundred' is the wordplay.
'made' indicates anagramming the letters.
'about' is an insertion indicator.
'hundred' becomes 'c' (Roman numeral).
'losers' is an anagram of 'lrosse'.
'a'+'c'='ac'
'lrosse' going around 'ac' is 'LACROSSE'.
(Other definitions for lacrosse that I've seen before include "Sport played with sticks" , "Score's uncertain after the Spanish" , "Game played with nets on sticks" , "Game played with netted sticks" , "Game played with a netted stick" .)