Lost (6)
'lost' is the definition.
(synonyms)
This is all the clue.
(Other definitions for astray that I've seen before include "Off course - wrong - misled" , "Off the correct path" , "wrong way" , "in the wrong place" , "Off one's route or lost" .)
'lost' is the definition.
(both can mean confused or in trouble)
This is all the clue.