Lost, alone, after pub crawl's initiation in the City (9)
I believe the answer is:
barcelona
'city' is the definition.
(Barcelona is an example)
'lost alone after pub crawl's initiation' is the wordplay.
'lost' indicates anagramming the letters.
'after' means one lot of letters go next to another.
'pub' becomes 'bar' (I've seen this before).
'initiation' suggests taking the first letters.
The initial letter of 'crawls' is 'c'.
'alone' is an anagram of 'elona'.
'bar'+'c'='barc'
'elona' after 'barc' is 'BARCELONA'.
'in the' acts as a link.
(Other definitions for barcelona that I've seen before include "9/11 [OLYMPIC VENUE]" , "City and province of Catalonia in NE Spain" , "Spanish city and seaport" , "Chief port of Spain" , "coastal city" .)