Lot to do as, running wild, this can be poisonous (9)
I believe the answer is:
toadstool
'wild this can be poisonous' is the definition.
Although both the answer and definition are singular nouns, I can't see how they can define each other.
'lot to do as running' is the wordplay.
'running' is an anagram indicator.
'lot'+'to'+'do'+'as'='lottodoas'
'lottodoas' with letters rearranged gives 'TOADSTOOL'.
Can you help me to learn more?
(Other definitions for toadstool that I've seen before include "Fungal growth" , "that could be poisonous" , "Poisonous fungus" , "Common fungus" , "what's poisonous maybe" .)