Loud drunkard is loaded (5)
I believe the answer is:
flush
'is loaded' is the definition.
(synonyms)
'loud drunkard' is the wordplay.
'loud' becomes 'f' (A musical term).
'drunkard' becomes 'lush' (lush is a kind of drunkard).
'f'+'lush'='FLUSH'
(Other definitions for flush that I've seen before include "Poker hand of same suit" , "Look ashamed < , maybe even promising hand" , "Rouse game and put to flight" , "winning hand at poker" , "Cleanse by running water" .)