Loud noise made by extremely ticklish subordinate (7)
I believe the answer is:
thunder
'loud noise' is the definition.
(I've seen this before)
'by extremely ticklish subordinate' is the wordplay.
'by' says to put letters next to each other.
'extremely' suggests removing the centre (only the extremes of the word are used).
'subordinate' becomes 'under' (similar in meaning).
'ticklish' with its middle removed is 'th'.
'th' next to 'under' is 'THUNDER'.
'made' acts as a link.
(Other definitions for thunder that I've seen before include "Clap" , "Booming noise after lightning" , "Rumble after lightning" , "Rail" , "Loud rumbling noise" .)