Love story from Cremona (7)
I believe the answer is:
'love story' is the definition.
(I know that love story can be written as romance)
'from cremona' is the wordplay.
'from' is an anagram indicator (the anagram comes from the same letters).
'cremona' is an anagram of 'ROMANCE'.
(Other definitions for romance that I've seen before include "Amorous relationship" , "Novel - love story" , "Affair of the heart" , "Feeling of mystery; love affair" , "Various languages such as French" .)