Low returns following daughter's ruin (4)
I believe the answer is:
doom
'ruin' is the definition.
(thesaurus)
'low returns following daughter's' is the wordplay.
'low' becomes 'moo' ('moo' can be a synonym of 'low').
'returns' says the letters should be written backwards.
'following' says to put letters next to each other.
'daughter' becomes 'd'.
'moo' in reverse letter order is 'oom'.
'oom' put after 'd' is 'DOOM'.
(Other definitions for doom that I've seen before include "Day of reckoning" , "Sentence" , "Condemn (to certain death?)" , "Catastrophe" , "Inescapable fate" .)