Lure first of tourists in Eastern Mediterranean resort (6)
I believe the answer is:
'lure' is the definition.
'first of tourists in eastern mediterranean resort' is the wordplay.
'first of tourists' becomes 't' (1st letter of 'tourists').
'in' means one lot of letters goes inside another.
'eastern' becomes 'e'.
'mediterranean resort' becomes 'nice' (French city on the Mediterranean).
't' put within 'enice' is 'ENTICE'.
(Other definitions for entice that I've seen before include "Lure, inveigle" , "Allure" , "act like clickbait" , "Attract or persuade with offer" , "alluring" .)