Mackey who played Physicist Barbie (4)

I believe the answer is:

emma

(Other definitions for emma that I've seen before include "Name of Nelson's Lady Hamilton" , "Retired chief in Ian Fleming" , "Jane Austen work - Ms Bunton, former Baby Spice" , "young woman in novel" , "Jane Austen heroine" .)

I've seen this clue in the USA Today.

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