Made off with title (4)
I believe the answer is:
dame
'title' is the definition.
(I have seen 'Female title ' mean 'dame' so perhaps 'title' could also mean 'dame')
'made off' is the wordplay.
'off' indicates an anagram.
'made' with letters rearranged gives 'DAME'.
'with' is the link.
(Other definitions for dame that I've seen before include "See 21" , "Pantomime female" , "eg Edna Everage" , "Man's panto role" , "Female equivalent of a knight" .)