Made soup with dopehead, that's uplifting God's work (4,3)
I believe the answer is:
opus dei
'god's work' is the definition.
('work of God' in Latin)
'made soup with dopehead that's uplifting' is the wordplay.
'made' indicates anagramming the letters.
'with' says to put letters next to each other.
'dopehead' becomes 'd' (head letter of 'dope').
'that's' becomes 'ie'.
'uplifting' says the letters should be written backwards.
'ie' in reverse letter order is 'ei'.
'soup' anagrammed gives 'opus'.
'opus'+'d'+'ei'='OPUS DEI'
(Other definitions for opus dei that I've seen before include "Group of believers" , "Oedipus (anag) - divine liturgy - international Roman Catholic organisation" , "prayers" , "A religious organisation" , "Religious group" .)