Made with care, perhaps, by Edward (7)
I believe the answer is:
created
'made' is the definition.
(creating is a kind of making)
'care perhaps by edward' is the wordplay.
'perhaps' indicates an anagram.
'by' is a charade indicator (letters next to each other).
'edward' becomes 'ted' (**).
'care' is an anagram of 'crea'.
'crea'+'ted'='CREATED'
'with' acts as a link.
(Other definitions for created that I've seen before include "Made a fuss" , "Brought into existence" , "Originated" , "Made, generated" , "Devised" .)