Mail off to city (4)
I believe the answer is:
lima
'to city' is the definition.
(Lima is an example)
'mail off' is the wordplay.
'off' is an anagram indicator.
'mail' anagrammed gives 'LIMA'.
(Other definitions for lima that I've seen before include "distant city" , "Mail it to Peruvian city" , "Mail to Peru'd capital" , "South American capital" , "Send mail out to S America" .)